Development of Novel Molecular Imaging Tools

We are designing, manufacturing and evaluating new fluorescent molecules (‘SmartProbes’) that can be used to characterise a range of distal lung diseases including pneumonia, acute respiratory distress syndrome (ARDS), pulmonary fibrosis and lung cancer. We are working on SmartProbes for detection of neutrophilic, monocyte and macrophage activation, MMP activity, epithelial senescence, T cell activity and bacterial detection.

To date we have translated 5 novel SmartProbes into in-patient studies and are now planning larger multi-site validation studies.